Dextran CLIO Magnetic Nanoparticles - Biotin, Fluorescent Dye

General Information
Fluorescent, Biotin functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-BIOTD) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran strands of 40 or 70 kDa in size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term stability. Biotin and fluorescence dye are covalently conjugated to the nanoparticle surface.
 
Features
Superparamagnetic
Fluorescently labeled (AFDye 488, AFDye 555, AFDye 647, or IR750 dye)
Highly biocompatible, non-toxic
Long term stable under physiological conditions
40 kDa and 70 kDa dextran coats are available
Easy loading of biomolecules such as Antibodies through Streptavidin-Biotin interaction
 
Applications
 
In vitroand in vivodual magnetic and fluorescence labels for cells and tissues.
Magnetic, fluorescence, or dual cell separation.
Probes for MRI.
 
Specifications
Iron Oxide Core Diameter: 8 – 10 nm
Hydrodynamic Diameter: 70 – 100 nm
Polydispersity Index (PDI): < 0.25
Magnetization:  5 – 30 emu/g (room temperature)
Fluorescent Dye: AF488, Cy3, Cy5, or IR750
Shelf life: > 1 year (4°C storage)
Supplied as liquid suspension in water